Placental Abruption

BMJ Best Practice Clinical Guideline Placental abruption. Last reviewed: Jun 2025.

Disclaimer

There is currently no dedicated NICE guideline specifically addressing placental abruption. The RCOG Green-top Guideline No. 63: Antepartum Haemorrhage (published 2011) includes placental abruption, but its coverage is non-specific and has not been updated in over 10 years.
 

Therefore, this article bases primarily on BMJ Best Practice clinical guidance​​​​​​.

 

Background Information

Separation of the placenta from the uterus prior to delivery.

  • Smoking
  • Cocaine use (and other stimulants)
  • Alcohol misuse
  • Low BMI

  • Hypertension - most common cause
  • Pre-eclampsia
  • Autoimmune disease (e.g. antiphospholipid syndrome)
  • Thrombophilia

  • Maternal age
    • < 20 y/o
    • >35 y/o
 
  • Previous placental abruption - strongest risk factors
  • Multiple pregnancy
  • Trauma to the abdomen
  • Polyhydramnios
  • Assisted reproductive technologies (e.g. IVF)

Classic triad of:
  • 'Woody' tender uterus
  • Vaginal bleeding (may not be present)
  • Maternal shock (tachycardia, hypotension etc.)
 
 

20% cases are concealed where the bleeding is trapped behind the placenta so there would be no or minimal vaginal bleeding.

Concealed abruptions can be particularly dangerous, as the severity can be underestimated (visible blood loss can be little, but internal bleeding is significant).

Gudielines

  • FBC (including haemoglobin and haematocrit)
  • Clotting studies

1st line: ultrasound 
  • NB detection rate ~12-25%

Perform continuous cardiotography
  • Fetal well-being is important in guiding management

Stabilise the mother and resuscitate as needed.

Definitive management depends on 1) fetal status and 2) weeks of gestation, with exceptions:
  • Unstable maternal status → urgent Caesarean section (regardless of fetal status and weeks of gestation)
  • Dead fetus → vaginal delivery (usually with induction)

References

Author: Adams Lau
Reviewer:
Last edited: 09/07/25