Infective Conjunctivitis

NICE CKS Conjunctivitis - infective. Last revised: Oct 2022.

Background Information

  • Viral conjunctivitis - 80% cases
    • Most common due to adenovirus
    • Other: Herpes simplexVaricella zosterMolluscum contagiosum, Epstein-Barr, coxsackie and enteroviruses
 
  • Bacterial conjunctivitis
    • Most common: Streptococcus pneumoniaeStaphylococcus aureus and Haemophilus influenzae

  • Watery discharge (and less than bacterial conjunctivitis)
  • Erythema of the conjunctiva, follicles on eyelid eversion
  • Lid oedema
  • Subconjunctival haemorrhage

  • Purulent / mucopurulent discharge
  • Cursting of the eyelids 
  • Eyelids stuck together on waking

Guidelines

Clinical diagnosis based on clinical features (see above).

Do not routinely take swabs

Avoid antibiotic prescription

Advise self-care measures
  • Cold compress around the eye area
  • Bathing / cleaning the eyelids with cotton wool soaked in sterile saline or boiled and cooled water to remove any discharge
  • Use of lubricating agents or artificial tears

Advise on the prevention of spread:
  • Washing hands frequently with soap and water
  • USe separate towels and flannels
  • Avoid close contact with others 

But there is NO NEED for exclusion from school / nursery / childminders unless an outbreak or cluster of cases occurs.

Advise the person that most cases of bacterial conjunctivitis are self-limiting and resolve within 5–7 days without treatment

If severe / require rapid solution / symptoms not resolved within 3 days: offer topical antibiotics
  • Chloramphenicol, or
  • Fusidic acid (safe in pregnancy)

There is NO NEED for exclusion from school / nursery / childminders unless an outbreak or cluster of cases occurs.

If no corneal staining with topical fluorescein and no red flags:
  • Stop contact lens use immediately and avoid until all symptoms have resolved
  • Bathing / cleaning the eyelids with cotton wool soaked in sterile saline or boiled and cooled water to remove any discharge
 
  • Consider topical antibiotic effective against gram –ve organisms
    • Aminoglycoside (e.g. gentamycin)
    • Fluoroquinolone (e.g. levofloxacin, moxifloxacin)

References

Author: Adams Lau
Reviewer:
Last edited: 20/07/25